PrEP for Trans Women

It is safe to take hormones while using PrEP or PEP. Many people use Truvada as PrEP, PEP, or as treatment for HIV, and Truvada does not reduce hormone levels. Although it's not expected that Descovy PrEP would reduce hormone levels, more research needs to be done to fully understand possible interactions.

However, hormones like estradiol can reduce Truvada PrEP levels some, therefore, it's important to take as close to every dose as possible.

Both Truvada PrEP and Descovy PrEP should be used daily until more data are collected.

Are you a person who:

• Worries about HIV?

• Does not use condoms during sex with partners of unknown HIV status?

• Recently had gonorrhea or syphilis?

• Wants to have sex without condoms with a partner who has HIV?

• Exchanges sex for money, food, housing, and/or drugs?

• Injects drugs and shares needles?

If you answered yes to any of these questions, click the chat bubble on the right to speak with us about your PrEP options!

These resources can help you understand PrEP and whether it’s right for you:

• Videos

  • Transgender women and sexual health (2:24 min) – Project Inform

  • Women, PrEP & sexual health (2:16 min) – Project Inform

  • Mujeres, PrEP y salud sexual (3:19 min) – Project Inform (Spanish)

• PrEP basics

  • PrEP for U.S. Trans Women – HIVE, a hub of positive reproductive and sexual health

  • Safer Sex for Trans Bodies – Human Rights Campaign (English and Spanish)

  • #WeAreAllWomen – HIVE

  • PrEP for Women palm cards – PleasePrEPMe.org

  • Is PrEP Right for Me? – HIVE

  • Black Women and PrEP – Black AIDS Institute

  • PrEP: Woman-Controlled HIV Prevention – HIVE

  • Getting PrEPped flow chart – Project Inform (English and Spanish)

  • PrEP Basics – CDC

  • PrEP for Trans Women: Transcending Barriers for Safer Pleasure - Project Inform

• In-depth info on PrEP and sexual health

  • PrEP and Transgender People - Positively Aware 

  • What is PrEP? – AIDS Foundation of Chicago (Spanish)

  • PrEPFacts.org – San Francisco AIDS Foundation (English and Spanish)

  • PrEP4Women – HIVE

  • PrEP for Women – The Well Project

• PrEP research

  • PrEP research and demonstration projects – AVAC

  • PrEP Watch – AVAC

  • No HIV infections over two years among MSM and transgender individuals taking event-driven PrEP - aidsmap

Search our PrEP provider directory by zip code to find a PrEP provider near you. 

Also, check out UCSF's Directory of Transgender Health Centers.

Online PrEP providers are also available.

• Clinician Consultation Center’s PrEPLine – Share this link with your medical provider if they are new to PrEP and would like expert clinical consultation by phone.

• Help Desk (if a provider refuses to prescribe PrEP) – Lambda Legal

• What to Do If Your Provider Says “No” to PrEP – Human Rights Campaign

• Getting PrEPped flow chart – Project Inform (English and Spanish)

• Resources for Covering the Costs of PrEP/PEP

A trained navigator can help you decide which option is right for you. Use the search function on our site to find a provider who also offers navigation assistance. Or, chat with us and let us help!

• PrEP Facts: Women’s Sexuality and HIV Prevention Facebook group

• HIVE's blog

Looking for local and regional PrEP info and tools for providers, navigators, and PrEP seekers? Check out our State Resources pages to find PrEP resources in your state.

Tools for remembering to take a daily pill: 

• Medisafe Meds and Pill Reminder (iPhone or Android)

• Every Dose, Every Day app (iPhone or Android)

• MyMedSchedule.com

• ¿Es la PPrE adecuada para mi? – HIVE

• Mujeres, PrEP y salud sexual – Project Inform

• PrEP para Mujeres: Una nueva opción para que las mujeres amen de manera más segura - Project Inform

• Transgender Women and Pre-Exposure Prophylaxis for HIV Prevention – National Center for Innovation in HIV Care

• The future of PrEP among transgender women: the critical role of gender affirmation in research and clinical practices – Journal of the International AIDS Society

• Transgender women & PrEP – American Academy of HIV Medicine

• PrEP for U.S. Trans Women – HIVE

• TransLine Transgender Medical Consultation Service – Project HEALTH/Lyon-Martin

• Do Ask, Do Tell – The Fenway Institute