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PrEP for Trans Women

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➔ PrEP, or pre-exposure prophylaxis, is a pill to help keep you HIV negative. When taken as prescribed, PrEP is highly effective. PrEP is safe and generally well tolerated. Most insurance plans (public and private) cover PrEP.

PrEP works for women, men, people of transgender experience, people of all sexual orientations and gender identities, youth, and people who inject drugs.

You can use PrEP alone or in combination with other prevention tools like condoms, PEP, and U=U to reduce your chances of getting HIV and take charge of your sexual health!

It is safe to take hormones while using PrEP or PEP. Many people use Truvada as PrEP, PEP, or as treatment for HIV, and Truvada does not reduce hormone levels. Although it's not expected that Descovy PrEP would reduce hormone levels, more research needs to be done to fully understand possible interactions.

However, hormones like estradiol can reduce Truvada PrEP levels some, therefore, it's important to take as close to every dose as possible.

Both Truvada PrEP and Descovy PrEP should be used daily until more data are collected.

Are you a person who:

  • Worries about HIV?

  • Does not use condoms during sex with partners of unknown HIV status?

  • Recently had gonorrhea or syphilis?

  • Wants to have sex without condoms with a partner who has HIV?

  • Exchanges sex for money, food, housing, and/or drugs?

  • Injects drugs and shares needles?

These resources can help you understand PrEP and whether it’s right for you:

Search our PrEP provider directory by zip code to find a PrEP provider near you. 

Also, check out UCSF's Directory of Transgender Health Centers.

Online PrEP providers are also available.

A trained navigator can help you decide which option is right for you. Use the search function on our site to find a provider who also offers navigation assistance. 

Looking for local and regional PrEP info and tools for providers, navigators, and PrEP seekers? Check out our State Resources pages to find PrEP resources in your state.

Tools for remembering to take a daily pill: